Epidermis and Acne
Acne is a chronic inflammatory disease of the hair follicles and sebaceous glands, and is sometimes even considered a physiological response in humans, since nearly everyone experiences acne of varying severity during their lifetime. It is more common in adolescent men and women, and women are slightly less than men, but the age is earlier than that of men. Epidemiological studies have shown that about 80% to 90% of adolescents have suffered from acne.
According to the pathogenesis of acne, acne is divided into three categories: ① Endogenous acne, including acne vulgaris, perioral dermatitis, acne aggregation, hidradenitis suppurativa, acne breakout, premenstrual acne, facial purulent skin diseases, etc.; ② Exogenous acne, mechanical acne, tropical acne, urticarial acne, summer acne, solar acne, drug-induced acne, chloracne, cosmetic acne and oily acne; ③ acne-like eruptions, including rosacea , keloid acne of the neck, gram-negative bacilli folliculitis, steroid acne, and acne-related syndromes. Among them, the acne concerned in the cosmetic field is acne vulgaris.
Acne is a chronic inflammatory pilosebaceous disease, and its pathogenesis has been basically clarified. The pathogenic factors can be summarized into four points: ①The sebaceous glands are active under the action of androgens, the sebum secretion increases, and the skin is greasy; ②The adhesion of the keratinocytes in the infundibulum of the hair follicle increases, which is the blockage of the opening; ③The propionibacterium acnes in the hair follicle sebaceous gland is abundant Reproduction, decomposition of sebum; ④ chemical and cellular mediators lead to dermatitis, and then suppuration, the destruction of hair follicles and sebaceous glands.
Post time: Jul-29-2022